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Infrastructural investments and their impact on Sustainable Development Goals

Neurofilament Light Protein as a Biomarker in Severe Mental Disorders: A Systematic Review

Severe mental disorders (SMDs), such as schizophrenia (SZ), bipolar disorder (BD), and major depressive disorder (MDD), are heterogeneous psychiatric diseases that impose a significant societal burden due to their chronic disabling nature. There are no objective and reliable diagnostic tests for SMDs; thus, there is an urgent need for specific biomarkers to improve diagnosis, treatment, and resource allocation. Neurofilaments, found in cerebrospinal fluid and blood, offer reliable diagnostic ...

Classification of colorectal cancer patients based on serum micronutrients: An exploratory investigation

Background: Colorectal cancer (CRC) is a growing global health challenge with a multifactorial etiology encompassing genetic susceptibility, nutrition, and inflammation in the bowel. Objective: To examine micronutrient status in CRC patients undergoing CRC resection. Design: We performed a case-control study including 13 consecutive CRC patients and 10 healthy controls (CTRL) comparing the serum levels of 29 micronutrients, namely Copper, Zinc, Selenium, Chromium, Manganese, Carnitine, Cholin...

Copper Dysmetabolism is Connected to Epithelial-Mesenchymal Transition: A Pilot Study in Colorectal Cancer Patients

Colorectal cancer (CRC) is among the most diagnosed cancers worldwide, whose risk of mortality is associated with the development of metastases to the liver, lungs, and peritoneum. Of note, CRC is highly dependent on copper to sustain its proliferation and aggressiveness. Copper acts not only as a pivotal cofactor for several cuproproteins but also as an allosteric modulator of kinases essential to fulfill the epithelial-to-mesenchymal-transition (EMT), the main mechanism driving cancer cell ...

Exchangeable Copper Excess and Zinc Deficiency in the Serum of Patients with Colorectal Cancer

Copper (Cu) and Zinc (Zn) are altered in colorectal cancer (CRC) but their association with the clinical classification of the tumor has not been fully explored. To examine the association of Cu and Zn homeostasis in the onset and severity of CRC, we performed an exploratory case-control study comparing the serum levels for Cu, the exchangeable component of Cu in serum (CuExc), Zn, the ratio between them (CuExc:Zn), ceruloplasmin [Cp, concentration (iCp) and its activity (eCp), Cp specific ac...

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Per ogni richiesta riferirsi esclusivamente a: Ufficio Ricerca Uniecampus

Ref. Catalogo: Dott. Pierangelo Tomaselli Contatti: catalogo.ricerca@uniecampus.it

Prodotti recenti

Infrastructural investments and their impact on Sustainable Development Goals

Neurofilament Light Protein as a Biomarker in Severe Mental Disorders: A Systematic Review

Classification of colorectal cancer patients based on serum micronutrients: An exploratory investigation

Copper Dysmetabolism is Connected to Epithelial-Mesenchymal Transition: A Pilot Study in Colorectal Cancer Patients

Exchangeable Copper Excess and Zinc Deficiency in the Serum of Patients with Colorectal Cancer

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