Abnormalities in the cyclic adenosine monophosphate (cAMP)-dependent phosphorylation system have been recently reported in patients with bipolar disorder. We evaluated the immunoreactivity of the regulatory and catalytic subunits of cAMP-dependent protein kinase (protein kinase A) and 1 of its substrates, Rap1, in platelets from untreated euthymic, manic, and depressed patients with bipolar disorder and healthy subjects.
Titolo: | Abnormalities of cyclic adenosine monophosphate signaling in platelets from untreated patients with bipolar disorder |
Autori: | |
Data di pubblicazione: | 1999 |
Rivista: | |
Handle: | http://hdl.handle.net/11389/28575 |
Appare nelle tipologie: | 1.1 Articolo in rivista |
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